Validity of Modelling Cerebral Malaria in Mice: Argument and Counter Argument

Validity of Modelling Cerebral Malaria in Mice: Argument and Counter Argument

The clinical manifestations of Plasmodium falciparum infection of humans that are collectively recognised as cerebral malaria produce profound changes in mental status and induce coma. The histopathological hallmark of this encephalopathy is the sequestration of cerebral capillaries and venules with both infected and uninfected erythrocytes. The underlying cause of cerebral malaria is the subje...

Counter Argument In Defence of Common Sense

Argument or no argument ?

We will call such adjuncts instances of the X or no X construction It was suggested in the middle 1980s by Alexis Manaster-Ramer that well-formed instances of X or no X involve a string X of unbounded length preceding or no, with an exact copy following (for a brief allusion to it in print, see Manaster-Ramer 1986). This claim has received hardly any discussion at all in the subsequent literatu...

Establishing an Argument-Based Validity Approach for a Low-Stake Test of Collocational Behavior

Most of the validation studies conducted across varying test application contexts are usually framed within the traditional conceptualization of validity and therefore lack a comprehensive framework to focus on test score interpretations and test score use. This study aimed at developing and validating a collocational behavior test (CBT), drawing on Kane's argument-based approach to validity. F...

The Deconstruction of Safety Arguments Through Adversarial Counter-Argument

The project Deconstructive Evaluation of Risk In Dependability Arguments and Safety Cases (DERIDASC) has recently experimented with techniques borrowed from literary theory as safety case analysis techniques (Armstrong & Paynter 2003, Armstrong 2003). This paper introduces our high-level method for “deconstructing” safety arguments. Our approach is quite general and should be applicable to diff...